Do you know certain excretory system diseases can also lead to the death of the individual? If the urinary system, a component of the excretory system, stop working, your body will start accumulating 800 to 2,000 ml urine each day and get overflooded in a few days!

In addition to the disposal of liquid and semisolid waste, your excretory system performs lots of other important functions, such as the removal of ammonia, urea, uric acid, carbon dioxide, excess water, inorganic ions, bile pigments, urochrome, and so on. Other jobs assigned to this body system include the storage of waste, detoxification of harmful substances and maintenance of homeostasis. An excretory system disease will impair some or all of such jobs assigned to the system.

Common Excretory System Diseases:

Around 80% of all the kidney stones cases result from the precipitation of calcium from the urine.

An excretory system disease refers to the damage or malfunctioning of any organ associated with the system, such as the kidneys, the bladder, the ureters, the urethra, the large intestine, the rectum and the anus. Some of the common excretory system diseases include kidney stones, bladder cancer, kidney failure, uremia, renal cell carcinoma, urinary tract obstruction, diabetic nephropathy, and so on.

Renal Calculi:

Also known as renal calculi, the kidney stones are the solid pieces of material that result from the precipitation of substances dissolved in the urine, mostly calcium. An individual suffering from the kidney stones disorder complains of intense pain in the back, groin or lower abdominal region. Other symptoms of the condition include renal colic, pain during urination and presence of blood in the urine. Depending on the stage and severity of the condition, the kidney stones can be removed through medical or surgical therapies.

Diabetic Nephropathy:

In the case of diabetic nephropathy, the kidney function is deteriorated due to complications from the diabetic mellitus. The reduced rate of glomerular filtration, increase in blood pressure and increased excretion of the protein albumin with the urine serves as clear signs of the onset of this disease.

The treatments for the diabetic nephropathy focus primarily on the bringing the blood pressure and the blood glucose level to the normal levels. A controlled diet and pharmacological interventions are often useful in treating the disease.


The medical condition, called uremia, results from the toxic effects of the accumulation of abnormally high concentrations of nitrogenous substances in the blood. The condition arises when the kidneys fail to expel (excrete) waste products through the urine.

Renal Cell Carcinoma:

The excretory system disease renal cells carcinoma is characterized by the presence of malignant epithelial cells in the kidneys. Did you know the renal cell carcinoma accounts for around 90% cases of all kidney cancers in adults?

The disease may occur due to both the genetic and environmental factors and requires proper treatment through radiation or surgery. As it does not respond well to chemotherapy, a surgical operation becomes necessary. Usually, the affected kidney tissue is removed.